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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KIAA1704
All Species:
23.64
Human Site:
S245
Identified Species:
43.33
UniProt:
Q8IXQ4
Number Species:
12
Phosphosite Substitution
Charge Score:
0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IXQ4
NP_061029.2
340
38142
S245
Q
E
A
R
K
S
S
S
K
K
D
E
E
H
I
Chimpanzee
Pan troglodytes
XP_509661
340
38139
S245
Q
E
A
R
K
S
S
S
K
K
D
E
E
H
I
Rhesus Macaque
Macaca mulatta
XP_001094145
344
38614
G249
Q
E
A
R
K
S
S
G
K
K
D
E
E
H
I
Dog
Lupus familis
XP_851499
342
38712
N247
Q
E
A
R
K
S
F
N
K
K
D
E
E
H
V
Cat
Felis silvestris
Mouse
Mus musculus
Q69ZC8
346
38936
S251
Q
E
A
R
K
S
F
S
K
K
D
E
E
N
I
Rat
Rattus norvegicus
Q4V893
348
39156
S253
Q
E
A
R
K
S
L
S
K
K
D
E
E
N
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514535
347
38704
S252
Q
D
A
K
K
S
I
S
K
D
D
E
E
R
V
Chicken
Gallus gallus
NP_001006270
350
39239
S255
E
E
A
K
K
S
T
S
K
D
N
E
E
M
V
Frog
Xenopus laevis
NP_001089474
337
37926
S242
Q
E
A
K
V
S
S
S
T
T
E
E
K
F
P
Zebra Danio
Brachydanio rerio
NP_001003473
405
45367
E309
Q
E
A
K
E
K
G
E
S
A
K
D
D
V
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_996214
349
39457
Q258
A
Q
V
K
Y
E
Q
Q
R
D
D
E
Q
E
S
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q93591
297
33204
A215
A
R
S
V
G
I
A
A
A
D
A
R
Q
A
A
Sea Urchin
Strong. purpuratus
XP_796639
403
45460
E299
A
E
K
R
R
I
E
E
T
Q
E
R
G
G
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
97.3
91.5
N.A.
89.5
87.3
N.A.
64.2
68.8
63.2
47.1
N.A.
26.9
N.A.
27.6
37.9
Protein Similarity:
100
100
98.5
96.1
N.A.
93.6
93.3
N.A.
75.2
80
75.8
60.2
N.A.
41.5
N.A.
44.7
53.8
P-Site Identity:
100
100
93.3
80
N.A.
86.6
80
N.A.
60
53.3
46.6
20
N.A.
13.3
N.A.
0
13.3
P-Site Similarity:
100
100
93.3
93.3
N.A.
93.3
93.3
N.A.
80
86.6
66.6
46.6
N.A.
40
N.A.
26.6
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
24
0
77
0
0
0
8
8
8
8
8
0
0
8
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
8
0
0
0
0
0
0
0
31
62
8
8
0
0
% D
% Glu:
8
77
0
0
8
8
8
16
0
0
16
77
62
8
0
% E
% Phe:
0
0
0
0
0
0
16
0
0
0
0
0
0
8
0
% F
% Gly:
0
0
0
0
8
0
8
8
0
0
0
0
8
8
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
31
0
% H
% Ile:
0
0
0
0
0
16
8
0
0
0
0
0
0
0
31
% I
% Lys:
0
0
8
39
62
8
0
0
62
47
8
0
8
0
8
% K
% Leu:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
8
% M
% Asn:
0
0
0
0
0
0
0
8
0
0
8
0
0
16
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
16
% P
% Gln:
70
8
0
0
0
0
8
8
0
8
0
0
16
0
0
% Q
% Arg:
0
8
0
54
8
0
0
0
8
0
0
16
0
8
0
% R
% Ser:
0
0
8
0
0
70
31
54
8
0
0
0
0
0
8
% S
% Thr:
0
0
0
0
0
0
8
0
16
8
0
0
0
0
0
% T
% Val:
0
0
8
8
8
0
0
0
0
0
0
0
0
8
24
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _